Originally posted in Cystic Fibrosis News From Medical News Today

A team of Johns Hopkins Children’s Center researchers has discovered that a protein involved in cystic fibrosis (CF) also regulates inflammation and cell death in emphysema and may be responsible for other chronic lung diseases…

Originally posted in Cystic Fibrosis News From Medical News Today

Inspire Pharmaceuticals, Inc. (NASDAQ: ISPH) announced that the results from its first Phase 3 clinical trial with denufosol tetrasodium for cystic fibrosis (CF), TIGER-1, have been published in the peer-reviewed publication, American Journal of Respiratory and Critical Care Medicine (AJRCCM)…

Originally posted in Cystic Fibrosis News From Medical News Today

Cystic fibrosis (CF) patients with normal to mildly impaired lung function may benefit from a new investigational drug designed to help prevent formation of the sticky mucus that is a hallmark of the disease, according to researchers involved in a phase 3 clinical trial of the drug…

Originally posted in Cystic Fibrosis News From Medical News Today

Like an overprotective parent on the first day of school, a targeting factor sometimes needs a little push to let go of its cargo. Scientists at the European Molecular Biology Laboratory (EMBL) in Grenoble, France, have visualised one such hand-over. They were the first to determine the structure of a ribosome-protein complex involved in carrying nascent proteins out of the cell…

Originally posted in Cystic Fibrosis News From Medical News Today

The University of British Columbia, in partnership with the Canadian Cystic Fibrosis Foundation (CCFF) and the Centre for Drug Research and Development (CDRD), has launched the Cystic Fibrosis Technology Initiative (CFTI) to advance Canadian technologies that will help combat cystic fibrosis (CF)…

Originally posted in Journal of Cystic Fibrosis

Abstract: Background: A meta-analysis was performed to examine differences in family mealtimes between families with and without a child with CF. Both global measures of family functioning during the mealtime and parent-child micro behaviors specific to feeding were compared to determine if one class of mealtime behaviors is more strongly affected.Methods: Of 41 studies identified, 10 studies across 4 independent samples met the criteria for study inclusion. All studies included observational methodology. The mean sample age ranged from 18.6months to 8years and 6months. The total aggregate sample size was 230 participants, 119 with CF and 111 comparison children.Results: Families with children with CF encounter more difficulties during mealtimes than comparison families, and the effects on overall family functioning are greater than for parent–child micro feeding behaviors.Conclusion: Findings suggest that future interventions should focus on the broader family context as well as behaviors specific to feeding.